Evaluation of Tpeak–Tend and QT intervals in Chagas’ Disease, Chronic Phase and Normal Electrocardiogram

Authors

  • Abilio Augusto Fragata Filho Instituto Dante Pazzanese de Cardiologia – Laboratório de Doença de Chagas – São Paulo (SP), Brazil
  • Claudia da Silva Fragata Instituto Dante Pazzanese de Cardiologia – Laboratório de Doença de Chagas – São Paulo (SP), Brazil
  • Angela Maria Lourenço Instituto Dante Pazzanese de Cardiologia – Laboratório de Doença de Chagas – São Paulo (SP), Brazil
  • Cristiane Castro Faccini Instituto Dante Pazzanese de Cardiologia – Laboratório de Doença de Chagas – São Paulo (SP), Brazil
  • João Ítalo Dias França Instituto Dante Pazzanese de Cardiologia – Laboratório de Doença de Chagas – São Paulo (SP), Brazil

Keywords:

Chagas’ disease, Tpeak–Tend interval, QT interval

Abstract

Introduction: Chagas’ disease lacks elements to predict which carriers will evolve into cardiac form and which will remain in undetermined form. Objective: To evaluate the relationship between electrocardiographic evolution and Tpeak–Tend and QT intervals, both corrected for heart rate, in chagasic patients with normal initial electrocardiogram. Method: Chagasic patients admitted to the institution until 2002 were retrospectively evaluated, and the electrocardiogram was normal at the first consultation. The Tpeak–Tend and QT intervals were measured in milliseconds at the V2 and V5 derivations, with the mean values corrected for heart rate (Bazett). The relationship of these values with the electrocardiographic evolution of the individuals was analyzed, considering the gender, time of evolution and whether they received benznidazole or not. Results: The corrected Tpeak–Tend interval showed no statistical significance among those who maintained or not normal electrocardiogram. The corrected QT interval, the treatment with benznidazole and the time of evolution showed significance for the maintenance of normal electrocardiogram. In the multivariate evaluation, treatment with benznidazole, the QTc interval and the time of evolution were independent variables for the maintenance of normal electrocardiogram. Conclusion: The Tpeak–Tend interval showed no predictor of electrocardiographic evolution. The increased QT interval favored changes.

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Published

16-04-2020

How to Cite

Fragata Filho, A. A. ., Fragata, C. da S. ., Lourenço, A. M. ., Faccini, C. C. ., & França, J. Ítalo D. . (2020). Evaluation of Tpeak–Tend and QT intervals in Chagas’ Disease, Chronic Phase and Normal Electrocardiogram. JOURNAL OF CARDIAC ARRHYTHMIAS, 32(4), 230–235. Retrieved from https://jca.org.br/jca/article/view/3373

Issue

Section

Clinical Arrythmia