Electrical stimulation in special clinical situations
DOI:
https://doi.org/10.24207/jca.v37il.3504Keywords:
Neurotransmitter Agents, Computer Peripherals, Implantable NeurostimulatorsAbstract
Introduction: Neuromodulation is an approach used to treat diseases that are refractory to clinical treatments by employing electrical and chemical stimulation techniques, especially in cardiac, neurological, and psychiatric disorders. Objective: This study aims to provide an overview of the latest developments in neuromodulation therapies that use electrical stimulation. Methods and results: The present study describes the most common neuromodulation techniques. Neuroplasticity is used to adjust the ions and neural excitability in response to central and peripheral nervous system stimulation. The spinal cord, dorsal root, and gastric stimulations are effective treatments for neuropathies, chronic pain, muscle spasticity, epilepsy, depression, cluster headaches, heart failure, and gastroparesis symptoms. Deep brain stimulation and invasive cortical stimulation are medical procedures used selectively to treat Parkinson’s disease, dystonia, obsessive-compulsive disorder, and chronic pain. Barostimulation therapy is beneficial in controlling refractory hypertension, reducing the risk of cardiovascular events, and improving overall quality of life. Repetitive Transcranial Magnetic Stimulation is a recommended treatment option for fibromyalgia, neuropathic pain, chronic headaches, treatment-resistant depression, generalized anxiety disorders, schizophrenia, and attention deficit disorder. While controlling obesity shows promise in regulating appetite and promoting satiety, more research is needed to understand the safety and efficacy of these therapies in various groups. Conclusion: Neuromodulation devices hold promise for treating diseases that do not respond to clinical treatments. Additional clinical trials and studies are required to understand it fully.
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Rauck R, Thomson S, RELIEF Study Group, NA, Chen L, Jain R. ID: 205630 Long-Term Safety of Spinal Cord Stimulation Systems: A Prospective, Global Registry of Chronic Pain Patients. Neuromodulation Technol Neural Interface. 2023;26(4):S26. https://doi.org/10.1016/j.neurom.2023.04.044 DOI: https://doi.org/10.1016/j.neurom.2023.04.044
Cruccu G, Garcia-Larrea L, Hansson P, Keindl M, Lefaucheur JP, Paulus W, et al. EAN guidelines on central neurostimulation therapy in chronic pain conditions. Eur J Neurol. 2016;23(10):1489–99. https://doi.org/10.1111/ene.13103 DOI: https://doi.org/10.1111/ene.13103
Knotkova H, Hamani C, Sivanesan E, Le Beuffe MFE, Moon JY, Cohen SP, et al. Neuromodulation for chronic pain. Lancet. 2021;397(10289):2111–24. https://doi.org/10.1016/s0140-6736(21)00794-7 DOI: https://doi.org/10.1016/S0140-6736(21)00794-7
Milosevic M, Marquez-Chin C, Masani K, Hirata M, Nomura T, Popovic MR, et al. Why brain-controlled neuroprosthetics matter: mechanisms underlying electrical stimulation of muscles and nerves in rehabilitation. Biomed Eng Online. 2020;19(1):81. https://doi.org/10.1186/s12938-020-00824-w DOI: https://doi.org/10.1186/s12938-020-00824-w
Gilmore C, Ilfeld B, Rosenow J, Li S, Desai M, Hunter C, et al. Percutaneous peripheral nerve stimulation for the treatment of chronic neuropathic postamputation pain: A multicenter, randomized, placebo-controlled trial. Reg Anesth Pain Med. 2019;44(6):637–45. https://doi.org/10.1136/rapm-2018-100109 DOI: https://doi.org/10.1136/rapm-2018-100109
Günter C, Delbeke J, Ortiz-Catalan M. Safety of long-term electrical peripheral nerve stimulation: review of the state of the art. J Neuroeng Rehabil. 2019;16(1):13. https://doi.org/10.1186/s12984-018-0474-8 DOI: https://doi.org/10.1186/s12984-018-0474-8
Deer TR, Mekhail N, Provenzano D, Pope J, Krames E, Leong M, et al. The appropriate use of neurostimulation of the spinal cord and peripheral nervous system for the treatment of chronic pain and ischemic diseases: the Neuromodulation Appropriateness Consensus Committee. Neuromodulation [Internet]. 2014 [cited 2023 Jul 2];17(6):515–50. https://doi.org/10.1111/ner.12208 DOI: https://doi.org/10.1111/ner.12208
Slangen R, Schaper NC, Faber CG, Joosten EA, Dirksen CD, Van Dongen RT, et al. Spinal cord stimulation and pain relief in painful diabetic peripheral neuropathy: A prospective two-center randomized controlled trial. Diabetes Care. 2014;37(11):3016–24. https://doi.org/10.2337/dc14-0684 DOI: https://doi.org/10.2337/dc14-0684
Kirketeig T, Schultheis C, Zuidema X, Hunter CW, Deer T. Burst Spinal Cord Stimulation: A Clinical Review. 2019 [cited 2023 Jul 4]; 20(Suppl1):S31-S40. https://doi.org/10.1093/pm/pnz003 DOI: https://doi.org/10.1093/pm/pnz003
Duarte R V., Nevitt S, McNicol E, Taylor RS, Buchser E, North RB, et al. Systematic review and meta-analysis of placebo/sham controlled randomised trials of spinal cord stimulation for neuropathic pain. Pain [Internet]. 2020 [cited 2023 Jul 4];161(1):24–35. https://doi.org/10.1097/j.pain.0000000000001689 DOI: https://doi.org/10.1097/j.pain.0000000000001689
Thomson S, MBBS, FRCA, FIPP, FFPMRCA Past President, International Neuromodulation Society. Spinal Cord Stimulation Its Role in Managing Chronic Disease Symptoms, Factsheet. Int Neuromodulation Soc [Internet]. 2016;1–4. Available from: https://www.neuromodulation.com/assets/documents/Fact_Sheets/fact_sheet_spinal_cord_stimulation.pdf
Strand NH, Burkey AR. Neuromodulation in the Treatment of Painful Diabetic Neuropathy: A Review of Evidence for Spinal Cord Stimulation. J Diabetes Sci Technol. 2021;16(2):332–40. https://doi.org/10.1177/19322968211060075 DOI: https://doi.org/10.1177/19322968211060075
Rigoard P, Roulaud M, Goudman L, Adjali N, Ounajim A, Voirin J, et al. Comparison of spinal cord stimulation vs. Dorsal root ganglion stimulation vs. association of both in patients with refractory chronic back and/or lower limb neuropathic pain: An international,prospective, randomized, double-blinded, crossover trial (BOOST-DRG Study). Med. 2022;58(1)7. https://doi.org/10.3390/medicina58010007 DOI: https://doi.org/10.3390/medicina58010007
Burlen J, Runnels M, Mehta M, Andersson S, Ducrotte P, Gourcerol G, et al. Efficacy of Gastric Electrical Stimulation for Gastroparesis: US/European Comparison. Gastroenterol Res. 2018;11(5):349-54. https://doi.org/10.14740/gr1061w DOI: https://doi.org/10.14740/gr1061w
González HFJ, Yengo-Kahn A, Englot DJ. Vagus Nerve Stimulation for the Treatment of Epilepsy. Neurosurg Clin N Am. 2019;30(2):219–30. https://doi.org/10.1016/j.nec.2018.12.005 DOI: https://doi.org/10.1016/j.nec.2018.12.005
O’Reardon JP, Cristancho P, Peshek AD. Vagus Nerve Stimulation (VNS) and Treatment of Depression: To the Brainstem and Beyond. Psychiatry (Edgmont) [Internet]. 2006;3(5):54–63. Available from: https://pubmed.ncbi.nlm.nih.gov/21103178/
Gaul C, Diener HC, Silver N, Magis D, Reuter U, Andersson A, et al. Non-invasive vagus nerve stimulation for PREVention and Acute treatment of chronic cluster headache (PREVA): A randomised controlled study. Cephalalgia. 2015;36(6):534–46. https://doi.org/10.1177/0333102415607070 DOI: https://doi.org/10.1177/0333102415607070
Normatizações C De, Markman Filho B, Sousa ACS, Issa AFC, Nascimento BR, Correa Filho H, et al. Diretrizes Brasileiras de Hipertensão Arterial – 2020 Diretrizes. 2021;116(3):516–658. Available from: http://departamentos.cardiol.br/sbc-dha/profissional/pdf/Diretriz-HAS-2020.pdf
Lohmeier TE, Irwin ED, Rossing MA, Serdar DJ, Kieval RS. Prolonged Activation of the Baroreflex Produces Sustained Hypotension. Hypertension. 2004;43(2 II):306–11. https://doi.org/10.1161/01.hyp.0000111837.73693.9b DOI: https://doi.org/10.1161/01.HYP.0000111837.73693.9b
Thrasher TN. Unloading arterial baroreceptors causes neurogenic hypertension. Am J Physiol - Regul Integr Comp Physiol. 2002;282:1044–53. https://doi.org/10.1152/ajpregu.00431.2001 DOI: https://doi.org/10.1152/ajpregu.00431.2001
Papademetriou V, Doumas M, Faselis C, Tsioufis C, Douma S, Gkaliagkousi E, et al. Carotid baroreceptor stimulation for the treatment of resistant hypertension. Int J Hypertens. 2011;2011:964394. https://doi.org/10.4061/2011/964394 DOI: https://doi.org/10.4061/2011/964394
Bisognano JD, Bakris G, Nadim MK, Sanchez L, Kroon AA, Schafer J, et al. Baroreflex activation therapy lowers blood pressure in patients with resistant hypertension: Results from the double-blind, randomized, placebo-controlled rheos pivotal trial. J Am Coll Cardiol. 2011;58(7):765–73. https://doi.org/10.1016/j.jacc.2011.06.008 DOI: https://doi.org/10.1016/j.jacc.2011.06.008
Stoll BJ, Hansen NI, Bell EF, Walsh MC, Carlo WA, Shankaran S, et al. HHS Public Access Author manuscript. 2016;314(10):1039–51. DOI: https://doi.org/10.1001/jama.2015.10244
Campagnole-santos MJ, Haibara AS. Reflexos cardiovasculares e hipertensão arterial. 2001;8(1):30–40. Available from: https://pesquisa.bvsalud.org/portal/resource/pt/lil-284125
Abraham WT, Zile MR, Weaver FA, Butter C, Ducharme A, Halbach M, et al. Baroreflex Activation Therapy for the Treatment of Heart Failure With a ReducedEjection Fraction. JACC Hear Fail. 2015;3(6):487–96. https://doi.org/10.1016/j.jchf.2015.02.006 DOI: https://doi.org/10.1016/j.jchf.2015.02.006
Kishi T. Deep and future insights into neuromodulation therapies for heart failure. J Cardiol. 2016;68(5):368–72. https://doi.org/10.1016/j.jjcc.2016.05.010 DOI: https://doi.org/10.1016/j.jjcc.2016.05.010
Antonenko D, Schubert F, Bohm F, Ittermann B, Aydin S, Hayek D, et al. tDCS-induced modulation of GABA levels and resting-state functional connectivity in older adults. J Neurosci. 2017;37(15):4065–73. https://doi.org/10.1523/jneurosci.0079-17.2017 DOI: https://doi.org/10.1523/JNEUROSCI.0079-17.2017
Oh J, Jang KI, Jeon S, Chae JH. Effect of Self-administered Transcranial Direct Stimulation in Patients with Major Depressive Disorder: A Randomized, Single-blinded Clinical Trial. Clin Psychopharmacol Neurosci. 2022;20(1):87–96. https://doi.org/10.9758/cpn.2022.20.1.87 DOI: https://doi.org/10.9758/cpn.2022.20.1.87
Karabanov AN, Saturnino GB, Thielscher A, Siebner HR. Can transcranial electrical stimulation localize brain function? Front Psychol.2019;10:213. https://doi.org/10.3389/fpsyg.2019.00213 DOI: https://doi.org/10.3389/fpsyg.2019.00213
Guo W, He Y, Zhang W, Sun Y, Wang J, Liu S, et al. A novel non-invasive brain stimulation technique: “Temporally interfering electrical stimulation.” Front Neurosci. 2023;17:1092539. https://doi.org/10.3389/fnins.2023.1092539 DOI: https://doi.org/10.3389/fnins.2023.1092539
Thair H, Holloway AL, Newport R, Smith AD. Transcranial direct current stimulation (tDCS): A Beginner’s guide for design and implementation. Front Neurosci. 2017;11:641. https://doi.org/10.3389/fnins.2017.00641 DOI: https://doi.org/10.3389/fnins.2017.00641
Wathen CA, Frizon LA, Maiti TK, Baker KB, Machado AG. Deep brain stimulation of the cerebellum for poststroke motor rehabilitation: From laboratory to clinical trial. Neurosurg Focus. 2018;45(2):E13. https://doi.org/10.3171/2018.5.focus18164 DOI: https://doi.org/10.3171/2018.5.FOCUS18164
Li MCH, Cook MJ. Deep brain stimulation for drug-resistant epilepsy. Epilepsia. 2018;59(2):273–90. https://doi.org/10.1111/epi.13964 DOI: https://doi.org/10.1111/epi.13964
Fernández-Pajarín G, Sesar Á, Relova JL, Ares B, Jiménez I, Gelabert-González M, et al. Parkinson’s Disease Symptoms Associated with Developing On-State Axial Symptoms Early after Subthalamic Deep Brain Stimulation. Diagnostics. 2022;12(4):1001. https://doi.org/10.3390/diagnostics12041001 DOI: https://doi.org/10.3390/diagnostics12041001
Benabid AL, Pollak P, Hoffmann D, Gervason C, Hommel M, Perret JE, et al. Long-term suppression of tremor by chronic stimulationof the ventral intermediate thalamic nucleus. Lancet. 1991; 337(8738): 403–6. https://doi.org/10.1016/0140-6736(91)91175-t DOI: https://doi.org/10.1016/0140-6736(91)91175-T
Lin X, Li H. Obesity: Epidemiology, Pathophysiology, and Therapeutics. Front Endocrinol (Lausanne). 2021;12:706978. https://doi.org/10.3389/fendo.2021.706978 DOI: https://doi.org/10.3389/fendo.2021.706978
Val-Laillet D, Aarts E, Weber B, Ferrari M, Quaresima V, Stoeckel LE, et al. Neuroimaging and neuromodulation approaches to study eating behavior and prevent and treat eating disorders and obesity. NeuroImage Clin. 2015;8:1–31. https://doi.org/10.1016/j.nicl.2015.03.016 DOI: https://doi.org/10.1016/j.nicl.2015.03.016
Laughlin M, Cooke B, Boutelle K, Savage CR, Kravitz A, Small D, et al. Neuroimaging and modulation in obesity and diabetes research: 10th anniversary meeting. Int J Obes. 2022;46:718–25. https://doi.org/10.1038/s41366-021-01025-8 DOI: https://doi.org/10.1038/s41366-021-01025-8
